thiamphenicol
Thiamphenicol
Product Name: Thiamphenicol
English Synonyms: sulfur ADM; Thiamphenicol chloramphenicol;
English name: thiamphenicol
English Synonyms: Methylsulfonyl chloramphenicol; Thiamphenicol
Category: medicine / chemical and intermediates
C A S Number: 15318-45-3
Molecular formula: C12H15Cl2NO5S
Molecular Weight: 356.22
Melting point: 163 ℃ -167 ℃
Rotation: -21 ° ~ -24 °
Heavy Metals: ≤ 10PPM
Loss on drying: ≤ 1.0%
Chloride: ≤ 0.02%
Residue on ignition: ≤ 0.1%
Quality Standard: CP
The appearance of traits: white to white crystalline powder or crystals
Product content: 99%
Packing specifications: 25kg / cardboard drum.
Product use: Thiamphenicol category as a broad-spectrum antibiotic chloramphenicol, and its chemical structure is similar with chloramphenicol, which replaced a sulfonyl nitro chloramphenicol, thus reducing its toxicity in vivo antimicrobial activity than chlorine toxins 2.5-5 times as strong. Against Gram-positive bacteria such as the lung-type bacteria, hemolytic streptococcus strong antimicrobial activity against gram-positive bacteria such as Neisseria gonorrhoeae, Neisseria meningitidis, Bacteroides lungs, E. coli, Vibrio cholerae and Shigella bacteria, such as influenza have a strong antibacterial effect on anaerobic bacteria family, Rickettsia, protozoa such as Entamoeba has some antibacterial effect, its mechanism with the same chloramphenicol. Mainly inhibit bacterial protein synthesis, oral absorption of the drug quickly, within two hours in the blood can reach the peak concentration, half-life of 5 hours, lasting more than chloramphenicol, bacteria and chloramphenicol to the goods between the full cross-resistance, tetracycline to the goods and drugs, some cross-resistance phenomenon.