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Chlorphenamine Meleate

Chlorphenamine Meleate

Chlorphenamine Meleate

Detailed Selling Lead Description
Model: 56-75-7
Min. Order: 1 ton
Chlorphenamine Meleate
API
Chlorphenamine Meleate is a bacteriostatic antibiotic originally derived from the bacterium Streptomyces venezuelae, isolated by David Gottlieb, and introduced into clinical practice in 1949.

It was the first antibiotic to be manufactured synthetically on a large scale. Chloramphenicol is effective against a wide variety of microorganisms; It is still very widely used in low income countries because it is exceedingly cheap, but has fallen out of favour in the West due to a very rare side effect: Aplastic anemia, which is uniformly fatal when it occurs.

Systematic (IUPAC) name
2,2-dichlor-N- [(aR, bR)-b-hydroxy-a-hydroxymethyl- 4-nitrophenethyl] acetamide
Identifiers
CAS number: 56-75-7
ATC code: D06AX02, D10AF03, G01AA05, J01BA01, S01AA01, S02AA01, S03AA08
PubChem: 298
DrugBank: EXPT00942
Chemical data
Formula: C11H12N2Cl2O5
Mol. Weight: 323.132
Pharmacokinetic data
Bioavailability: 75 to 90%
Metabolism: Hepatic
Half life: 1.5 to 4.0 hours
Excretion: Renal
Therapeutic considerations
Pregnancy cat.: C (A topical)
Legal status: Occular P, else POM (UK)
Routes: Ocular, oral, IV, IM

Chloramphenicol
CAS: 56-75-7
Quality standard: CP2000/BP2000/USP26/EP4
Usage: Pharmaceutical raw material
Packing: 25kg/fiber drum, or 25kg/carton, or according to customers' requirement.
Certificate of Analysis: If needed, please fell free to contact us

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