Chitosan
9012-76-4
Chitosan
CAS: 9012-76-4
Formula: (C6H11NO4)N
Description: Chitosan is a linear polysaccharide composed of randomly distributed
β-(1-4)-linked D-glucosamine (deacetylated unit) and N-acetyl-D-glucosamine(acetylated unit). It is made by treating shrimp and other crustacean shells with the alkali sodium hydroxide. As a soluble dietary fiber, it increases gastrointestinal lumen viscosity and slows down the emptying of the stomach. It alters bile acid composition, increasing the excretion of sterols and reducing the digestibility of ilealfats. It is unclear how chitosan does this, but the currently favored hypotheses involve the increase of intestinal viscosity or bile acid-binding capacity. Chitosan is relatively insoluble in water, but can be dissolved by dilute acids, which would make it a highly-viscous dietary fiber. Such fibers might inhibit the uptake of dietary lipids by increasing the thickness of the boundary layer of the intestinal lumen, which has been observed in animal experiments. Having very few acetyl groups, chitosan contains cationic groups. This may cause chitosan to have bile acid-binding capacity, which causes mixed micelles to be entrapped or disintegrated in the duodenum and ileum.This would interrupt bile acid circulation, causing reduced lipid absorption and increased sterol excretion, which has also been observed in animal experiments.
Package:25KG/drum