Pharmaceutical intermediates
Tilmicosin Phosphate 磷酸替米考星
Appearance White or faint yellow powder
Identification
1、 should comply with the phosphate identification test
2、 HPLC: the retention time obtain from the test solution corresponds to that obtained from the standard solution
3、 Infra-red spectrum: infra-red spectrum of the sample corresponds to that of the reference standard
pH 5.5--7.5
Water ≤5.0%
Individual related substance ≤3.0%
Total related substance ≤10%MAX
Cis-isomer 82.0%--88.0%
Tran-isomer 12.0%--18.0%
Assay (on dried basis) ≥75.0%