Erlotinib HCL
Erlotinib is used to treat advanced non-small cell lung cancer (NSCLC), an aggressive type of lung cancer. NSCLC the most common type of lung cancer. It is most often caused by exposure to tobacco smoke. The World Health Organization (WHO) estimates that NSCLC is responsible for about 880,000 deaths each year. Lung cancer is the leading cause of cancer deaths in the United States. The American Cancer Society estimates that lung cancer is responsible for 28% of cancer deaths or the deaths of more than 160,000 individuals annually. Erlotinib is not a first-line treatment for NSCLC, and is used only after the cancer has failed to respond or stopped responding to at least one round of chemotherapy.

Chremical Name: N -(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)- 1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazole carboxamide monohydrate.

CAS No.: [863127-77-9]

Molecular Formula: C 22H 26ClN7O2S.H 2 O

Molecular Weight: 506.02

Description:Off-white to pale yellow power .

Solubility: Insoluble in water, slightly soluble in methanol and ethanol.

Related substances:Any single impurities: NMT0.5%; Total impurities: NMT1.0%

Assay(HPLC):min 99%