Calcipotriene (Treat dermatosis)
Calcipotriene (Treat dermatosis)

Synonyms: Calcipotriene; (1R,3S,5Z)-5-[(2E)-2-[1-[(E,2R,5R)-5-Cyclopropyl-5-hydroxypent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol

Molecular Formula: C27H40O3

Molecular Weight: 412.60

CAS Registry Number: 112828-00-9

Usage and efficacy: Available as a cream, ointment or scalp solution (50 μg/mL), calcipotriol is applied twice daily to plaque psoriasis on the body or scalp, but not the face. Improvement is usually detectable within 2 weeks. Most patients show some improvement, slightly more so than is seen with the use of corticosteroids alone. Tachyphylaxis does not occur, an improvement over glucocorticoid therapy